Breaking News
Loading...
October 25, 2013

Info Post
     
      Researchers have found that the role of melanin pigmentation accumulated by various drugs such as nicotine ( polyacylic mixture ) contained in a cigarette . When nicotine plays a role in the affinity of melanin in the hair , also play a role in the affinity of melanin present in the skin and other tissues ( such as the oral mucosa ) . Nicotine contained in cigarettes will directly stimulate melanocytes to meproduksi melanosomes , which will result in increased deposition of melanin pigment in melanosis bacilli with various dosage amount of melanin .
      Oral melanosis occur deposition of melanin in the basal cell layer of the epithelium lining the oral mucosa pasa . Melanin pigmentation of mucous membranes in the mouth is normally seen around the mouth area mukosa.Melanosis is a lesion that is reversible , can be lost when stopping smoking.      Smoker melanosis occurring in ethnic groups blacks and whites , which increased pigmentation that is directly related to smoking ( number of cigarettes smoked per day , type of cigarettes smoked , duration of smoking and how a person smoke cigarettes ) . Gingival pigmentation increases with tobacco consumption . Any hypothesis which found that the likelihood of nicotine stimulates the activity of melanocytes and melanin production of melanin or associated with dangerous ties to tobacco cigarettes .      Clinical picture seen in smokerr 's melanosis is showing diffuse brown spot the size of a few centimeters and are usually found on the anterior mandibular gingiva and buccal mucosa . On pipe smokers showed pigmentation on the buccal mucosa . In some people use cigarettes as cigarettes are placed in the oral cavity , will show the pigmentation of the hard palate . These lesions do not have symptoms , the changes do not show premalignat .      Teeth in smokers melanosis showed a light brown to dark brown and accompanied with circumstances accompanying halitosis is caused by changes in blood flow and a reduction in spending mengakibatnya oral saliva becomes dry and more anaerobic . Smoker's melanosis usually occurs in the Caucasian race showed prevalence of 31% in the fixed gingiva .      
 Differential diagnosis of Smoker's melanosis is Addison's Disease , Albright Syndrome , Hemochromatosis , Neurofibromatosis , Oral Malignant Melanoma , Oral nevi .

      The treatment is carried out is getting patients to quit smoking for health reasons . Quitting smoking usually indicates the loss of melanosis during a period of up to several years . Smoking cessation program in consultation with and supported by the family environment will benefit .

0 comments: